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Coloproctology and Endoscopic Surgery in Uzbekistan

Fatal error: Uncaught PDOException: SQLSTATE[HY000] [2002] Connection refused in /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/doctrine/dbal/lib/Doctrine/DBAL/Driver/PDOConnection.php:38 Stack trace: #0 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/doctrine/dbal/lib/Doctrine/DBAL/Driver/PDOConnection.php(38): PDO->__construct('mysql:host=loca...', 'user_coloprocuz', 'rT3wI2tI4c', Array) #1 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connectors/Connector.php(67): Doctrine\DBAL\Driver\PDOConnection->__construct('mysql:host=loca...', 'user_coloprocuz', 'rT3wI2tI4c', Array) #2 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connectors/Connector.php(100): Illuminate\Database\Connectors\Connector->createPdoConnection('mysql:host=loca...', 'user_coloprocuz', 'rT3wI2tI4c', Array) #3 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connectors/Connector.php(50): Illuminate\Database\Connectors\Connector->tryAgainIfCausedByLostConnection(Object(Doctrine\DBAL\Driver\PDO\Exception), 'mysql:host=loca...', 'user_coloprocuz', 'rT3wI2tI4c', Array) #4 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connectors/MySqlConnector.php(24): Illuminate\Database\Connectors\Connector->createConnection('mysql:host=loca...', Array, Array) #5 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connectors/ConnectionFactory.php(184): Illuminate\Database\Connectors\MySqlConnector->connect(Array) #6 [internal function]: Illuminate\Database\Connectors\ConnectionFactory->Illuminate\Database\Connectors\{closure}() #7 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(926): call_user_func(Object(Closure)) #8 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(485): Illuminate\Database\Connection->getPdo() #9 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(664): Illuminate\Database\Connection->Illuminate\Database\{closure}('UPDATE sessions...', Array) #10 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(745): Illuminate\Database\Connection->runQueryCallback('UPDATE sessions...', Array, Object(Closure)) #11 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(725): Illuminate\Database\Connection->tryAgainIfCausedByLostConnection(Object(Illuminate\Database\QueryException), 'UPDATE sessions...', Array, Object(Closure)) #12 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(634): Illuminate\Database\Connection->handleQueryException(Object(Illuminate\Database\QueryException), 'UPDATE sessions...', Array, Object(Closure)) #13 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(496): Illuminate\Database\Connection->run('UPDATE sessions...', Array, Object(Closure)) #14 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Capsule/Manager.php(200): Illuminate\Database\Connection->affectingStatement('UPDATE sessions...', Array) #15 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/classes/db/DAO.inc.php(138): Illuminate\Database\Capsule\Manager::__callStatic('affectingStatem...', Array) #16 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/classes/session/SessionDAO.inc.php(104): DAO->update('UPDATE sessions...', Array) #17 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/classes/session/SessionManager.inc.php(185): SessionDAO->updateObject(Object(Session)) #18 [internal function]: SessionManager->write('fbcc539cfa7b244...', 'csrf|a:2:{s:9:"...') #19 [internal function]: session_write_close() #20 {main} Next Doctrine\DBAL\Driver\PDO\Exception: SQLSTATE[HY000] [2002] Connection refused in /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/doctrine/dbal/lib/Doctrine/DBAL/Driver/PDO/Exception.php:18 Stack trace: #0 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/doctrine/dbal/lib/Doctrine/DBAL/Driver/PDOConnection.php(42): Doctrine\DBAL\Driver\PDO\Exception::new(Object(PDOException)) #1 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connectors/Connector.php(67): Doctrine\DBAL\Driver\PDOConnection->__construct('mysql:host=loca...', 'user_coloprocuz', 'rT3wI2tI4c', Array) #2 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connectors/Connector.php(100): Illuminate\Database\Connectors\Connector->createPdoConnection('mysql:host=loca...', 'user_coloprocuz', 'rT3wI2tI4c', Array) #3 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connectors/Connector.php(50): Illuminate\Database\Connectors\Connector->tryAgainIfCausedByLostConnection(Object(Doctrine\DBAL\Driver\PDO\Exception), 'mysql:host=loca...', 'user_coloprocuz', 'rT3wI2tI4c', Array) #4 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connectors/MySqlConnector.php(24): Illuminate\Database\Connectors\Connector->createConnection('mysql:host=loca...', Array, Array) #5 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connectors/ConnectionFactory.php(184): Illuminate\Database\Connectors\MySqlConnector->connect(Array) #6 [internal function]: Illuminate\Database\Connectors\ConnectionFactory->Illuminate\Database\Connectors\{closure}() #7 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(926): call_user_func(Object(Closure)) #8 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(485): Illuminate\Database\Connection->getPdo() #9 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(664): Illuminate\Database\Connection->Illuminate\Database\{closure}('UPDATE sessions...', Array) #10 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(745): Illuminate\Database\Connection->runQueryCallback('UPDATE sessions...', Array, Object(Closure)) #11 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(725): Illuminate\Database\Connection->tryAgainIfCausedByLostConnection(Object(Illuminate\Database\QueryException), 'UPDATE sessions...', Array, Object(Closure)) #12 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(634): Illuminate\Database\Connection->handleQueryException(Object(Illuminate\Database\QueryException), 'UPDATE sessions...', Array, Object(Closure)) #13 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(496): Illuminate\Database\Connection->run('UPDATE sessions...', Array, Object(Closure)) #14 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Capsule/Manager.php(200): Illuminate\Database\Connection->affectingStatement('UPDATE sessions...', Array) #15 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/classes/db/DAO.inc.php(138): Illuminate\Database\Capsule\Manager::__callStatic('affectingStatem...', Array) #16 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/classes/session/SessionDAO.inc.php(104): DAO->update('UPDATE sessions...', Array) #17 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/classes/session/SessionManager.inc.php(185): SessionDAO->updateObject(Object(Session)) #18 [internal function]: SessionManager->write('fbcc539cfa7b244...', 'csrf|a:2:{s:9:"...') #19 [internal function]: session_write_close() #20 {main} Next Illuminate\Database\QueryException: SQLSTATE[HY000] [2002] Connection refused (SQL: UPDATE sessions SET user_id = ?, ip_address = 216.73.216.121, user_agent = Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com), created = 1750997513, last_used = 1750997513, remember = 0, data = csrf|a:2:{s:9:"timestamp";i:1750997514;s:5:"token";s:32:"fecf0af8e800948110b7bd528636047d";}, domain = www.coloproc.uz WHERE session_id = fbcc539cfa7b244445322cf969b3c2d3) in /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php:671 Stack trace: #0 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(745): Illuminate\Database\Connection->runQueryCallback('UPDATE sessions...', Array, Object(Closure)) #1 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(725): Illuminate\Database\Connection->tryAgainIfCausedByLostConnection(Object(Illuminate\Database\QueryException), 'UPDATE sessions...', Array, Object(Closure)) #2 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(634): Illuminate\Database\Connection->handleQueryException(Object(Illuminate\Database\QueryException), 'UPDATE sessions...', Array, Object(Closure)) #3 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(496): Illuminate\Database\Connection->run('UPDATE sessions...', Array, Object(Closure)) #4 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Capsule/Manager.php(200): Illuminate\Database\Connection->affectingStatement('UPDATE sessions...', Array) #5 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/classes/db/DAO.inc.php(138): Illuminate\Database\Capsule\Manager::__callStatic('affectingStatem...', Array) #6 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/classes/session/SessionDAO.inc.php(104): DAO->update('UPDATE sessions...', Array) #7 /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/classes/session/SessionManager.inc.php(185): SessionDAO->updateObject(Object(Session)) #8 [internal function]: SessionManager->write('fbcc539cfa7b244...', 'csrf|a:2:{s:9:"...') #9 [internal function]: session_write_close() #10 {main} thrown in /var/www/www-root/data/www/journals/coloproc.uz/public/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php on line 671

Coloproctology and Endoscopic Surgery in Uzbekistan

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STUDYING THE SIGNIFICANCE OF THE INTESTINAL LYMPHATIC SYSTEM IN EXPERIMENTALLY CREATED ULCERATIVE COLITIS MODEL FOR THE USE OF LYMPHOTROPIC THERAPY IN THE COMPLEX OF TREATMENT IN THIS PATHOLOGY